Characteristic	I, T1				I, T2				I, T3				I, T4				II, T1				II, T2				II, T3				II, T4				III, T1				III, T2				III, T3				III, T4
	N	Drug A N = 81	Drug B N = 91	p-value2	N	Drug A N = 81	Drug B N = 101	p-value2	N	Drug A N = 111	Drug B N = 71	p-value2	N	Drug A N = 81	Drug B N = 71	p-value2	N	Drug A N = 141	Drug B N = 91	p-value2	N	Drug A N = 81	Drug B N = 91	p-value2	N	Drug A N = 51	Drug B N = 61	p-value2	N	Drug A N = 51	Drug B N = 121	p-value2	N	Drug A N = 61	Drug B N = 71	p-value2	N	Drug A N = 91	Drug B N = 101	p-value2	N	Drug A N = 61	Drug B N = 81	p-value2	N	Drug A N = 101	Drug B N = 81	p-value2
Tumor Response	17	1 (13%)	5 (56%)	0.13	17	3 (38%)	1 (11%)	0.3	18	4 (36%)	3 (43%)	>0.9	15	0 (0%)	4 (57%)	0.026	22	3 (21%)	3 (38%)	0.6	16	1 (14%)	3 (33%)	0.6	9	1 (25%)	3 (60%)	0.5	16	2 (40%)	3 (27%)	>0.9	13	3 (50%)	3 (43%)	>0.9	19	2 (22%)	3 (30%)	>0.9	13	3 (60%)	1 (13%)	0.2	18	5 (50%)	1 (13%)	0.2
1 n (%)
2 Fisher’s exact test