Pipelines & Software

Ask For Help

Publications

02/14/2024 - Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models
02/07/2024 - Rapid anti-myeloma activity by T cells expressing an anti-BCMA CAR with a human heavy-chain-only antigen-binding domain
02/01/2024 - Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer
02/01/2024 - KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma
01/01/2024 - Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection
01/01/2024 - Effects of a humanized CD47 antibody and recombinant SIRP? proteins on triple negative breast carcinoma stem cells
01/01/2024 - Generation of murine tumor models refractory to ?PD-1/-L1 therapies due to defects in antigen processing/presentation or IFN? signaling using CRISPR/Cas9
12/01/2023 - Berzosertib plus topotecan vs topotecan alone in patients with relapsed small cell lung cancer: a randomized clinical trial
11/10/2023 - Single-cell RNA sequencing reveals cancer stem-like cells and dynamics in tumor microenvironment during cholangiocarcinoma progression
10/19/2023 - UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancer
10/01/2023 - Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
09/01/2023 - Transcriptional landscape of Kaposi sarcoma tumors identifies unique immunologic signatures and key determinants of angiogenesis
09/01/2023 - Tumors produce glucocorticoids by metabolite recycling, not synthesis, and activate Tregs to promote growth
08/01/2023 - Transcription factor EGR2 controls homing and pathogenicity of T(H)17 cells in the central nervous system
08/01/2023 - Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells
07/01/2023 - SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck