An Introduction to Gene Set Enrichment Analysis (GSEA) and the Molecular Signatures Database (MSigDB)

About this Class

Since its release in September 2005, the Gene Set Enrichment Analysis (GSEA) software and its companion gene set collections, the Molecular Signatures Database (MSigDB), have been invaluable resources for interpreting the biological significance of expression changes in large transcriptomic datasets. These tools enable the computation of "enrichment scores" to detect coordinated changes in gene expression programs in response to different perturbations.

In this webinar, we will provide an overview of the GSEA method, discuss best practices for analyzing various types of input data, and explore the wide range of resources available in the Molecular Signatures Database for analyzing both human and model organism data. Additionally, we will offer a sneak peek into several upcoming enhancements to the GSEA-MSigDB ecosystem.

For questions contact Daoud Meerzaman or Mel Nisonger.