Gene Expression in Health and Disease: The Single-Cell Perspective
When: Jan. 3rd, 2024 12:00 pm - 1:00 pm
Learning Level: Any
To Know
About this Class
on Wednesday, January 3rd at noon in Building 41, Conference Room C507/C509 and online. In-person attendance is encouraged.
Dr. Larson's research is focused on understanding gene expression in eukaryotic cells, starting from the mechanistic behavior of individual macromolecules and proceeding to their regulation in cells and tissue. His laboratory utilizes a battery of biophysical, molecular and genomic approaches, including single-molecule microscopy, RNA visualization in fixed and living cells, computational modeling of gene regulation, and nascent RNA sequencing. Dr. Larson helped pioneer in vivo single-molecule studies of transcription and splicing. The view that has emerged from these studies is that gene regulation is a dynamic process resulting in stochastic variation within populations. His current work is focused on applying these experimental and theoretical approaches to the study of hematopoiesis in health and disease through the trans-NIH Myeloid Malignancies Program.
For those unable to attend in person, this seminar will also be available via WebEx. See below for information on the WebEx session. For additional information on this seminar, please contact Lori Holliday at hollidal@mail.nih.gov.