Distinguished Speakers Seminar Series
Hematopoietic stem cell-intrinsic and -extrinsic contribution to aging and clonal hematopoiesis
When: Sep. 14th, 2023 1:00 pm - 2:00 pm
Presented By: Jennifer Trowbridge (The Jackson Lab)
Jennifer Trowbridge, Ph.D.
Associate Professor, The Jackson Laboratory
Professor, The Dattels Family Chair
Scholar of the Leukemia and Lymphoma Society
About this Class
While there is a positive correlation between cancer and aging, the mechanisms underlying this relationship remain unclear. Clonal hematopoiesis, a benign condition that is both associated with aging and predisposes to increased risk of development of blood cancers, presents an opportunity to understand the connection between cancer and aging. This seminar will discuss emerging discoveries of mechanisms acting within the hematopoietic stem cells as well as alterations in the bone marrow microenvironment that promote clonal hematopoiesis and transformation to blood cancers.