About this Class

While there is a positive correlation between cancer and aging, the mechanisms underlying this relationship remain unclear. Clonal hematopoiesis, a benign condition that is both associated with aging and predisposes to increased risk of development of blood cancers, presents an opportunity to understand the connection between cancer and aging. This seminar will discuss emerging discoveries of mechanisms acting within the hematopoietic stem cells as well as alterations in the bone marrow microenvironment that promote clonal hematopoiesis and transformation to blood cancers.