Novel Chemical Approaches for Targeting Fusion Oncoproteins: Computational Tools and Strategies for Rational Degrader Design

About this Class

The goal of this webinar series is to enhance understanding within the NCI and the research community of opportunities for targeting fusion oncoproteins through emerging chemoproteomic methods. This presentation will focus on computational tools and strategies for rational degrader design to target fusion oncoproteins. Speaker: Huan Rui, Ph.D. Senior Scientist, Computational Chemistry Dr. Rui is a senior scientist at Amgen specializing in computational chemistry. Dr. Rui currently leads the computational efforts for the induced proximity platform at Amgen, where her research interests include using molecular dynamics and free energy simulations to study biological systems and applying machine-learning techniques to augment physics-based modeling.