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Ingenuity Pathway Analysis (IPA)

Ingenuity® Pathway Analysis (IPA®) is a powerful analysis and search tool that uncovers the significance of ‘omics data and identifies new targets or candidate biomarkers within the context of biological systems. IPA has broadly been adopted by the life science research community and is cited in thousands of articles for the analysis, integration, and interpretation of data derived from ‘omics experiments, such as RNA-seq, small RNA-seq, microarrays including miRNA and SNP, metabolomics, proteomics, and small scale experiments.


  •  Commercial
  •  Web-Based

Ingenuity Pathway Analysis (IPA)

High Impact Features and Functionality in IPA
Analyze your high throughput data to understand mechanism and function

  • Gain biological context and understanding from microarray and proteomics data
  • Analyze changes in biological states across time and dosages

Build your own pathways

  • Create customized pathways for your targets, biomarkers, processes, and diseases of interest
  • Integrate your proprietary biological relationships into IPA pathways
  • Analyze your customized pathways to derive biological function
  • Compute "shortest paths" between genes or sets of genes

Use IPA as your everyday tool for biological search

  • Search based on genes, proteins, diseases, processes, functions, protein family, tissue, sub-cellular location, drug and more. Expand search results to elucidate pathways and function.

Personalize and share your IPA experience

  • Share your analyses and personalized pathways with colleagues
  • Create, store, and manage customized lists of genes and proteins
  • Generate high-resolution images for publication and presentations
  • Create bibliography of pathway information

Leverage the largest source of expert curated pathways content

  • Experience the impact of the unparalleled quality of 100% expert curated pathway content
  • Leverage vast library of canonical signaling and metabolic pathways
  • Integrate large repository of FDA approved drug information in your pathway analysis

Access Information:
Ingenuity Pathways Analysis is now available to all researchers affiliated with the NCI. Please use the registration link below to initiate your user account (NCI affiliated e-mail address required).
Enrollment is open to all researchers within the NCI. You must first contact the NIH Computer Helpdesk to be placed on the list of authorized NCI users. Then you can proceed to the link shown below to activate your private user account:
Help Desk Telephone: 301-496-4357 (open 6:00 am - 6:00 pm)
Email: (link sends e-mail)
Web: (link is external)