Distinguished Speakers Seminar Series
A More Comprehensive Landscape of RNA Alterations in Cancer with Long-read Sequencing
When: Jun. 6th, 2024 1:00 pm - 2:00 pm
Seminar Series Details:
About Angela Brooks, Ph.D., (UCSC)
Professor, Biomolecular Engineering
Postdoctoral Fellow,
Dana-Farber Cancer Institute/Broad Institute with Matthew Meyerson
Ph.D., Molecular and Cell Biology,
UC Berkeley with Steven Brenner
B.S., Biology with Specialization in Bioinformatics,
UC San Diego
About this Class
The Brooks Lab developed a computational tool called FLAIR (Full-Length Alternative Isoform Analysis of RNA) to produce confident transcript isoforms from long-read RNA-seq data with the aim of alternative isoform detection and quantification. With an increase in the usage of long-read RNA-seq, there is a growing need for a systematic evaluation of this approach. We are part of an international community effort called the Long-read RNA-seq Genome Annotation Assessment Project (LRGASP) to perform such an evaluation. The Brooks Lab is extending FLAIR to incorporate sequence variation, RNA editing, and RNA modification in isoform detection as well as detection of complex gene fusions from long-read sequencing data.
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- Meeting number:
- 2311 656 4503
- Password:
- ySkM7uW6B$5
- Join by video system
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Dial 23116564503@cbiit.webex.comYou can also dial 173.243.2.68 and enter your meeting number.
- Join by phone
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1-650-479-3207 Call-in number (US/Canada)Access code: 2311 656 4503