AmpliconSuite: Enabling Analysis of Focal Amplificaitons in Cancer Genomes
To Know
Where:
Online
Organizer:
CBIIT
Presented By:
Jens Luebeck PhD (UCSD)
About this Class
|
During this webinar, Dr. Jens Luebeck, a member of one of the winning 2022 Grand Cancer Challenges teams an Associate Project Scientist of computer science at UC San Diego, will show you how to: |
- detect and classify focal amplification mechanisms (including ecDNA and breakage-fusion-bridge cycles) directly from your WGS data.
- distinguish structural subtypes of amplifications to better characterize tumor heterogeneity and potential resistance mechanisms in your samples.
- access and explore pre-computed ecDNA predictions across NCI-funded cancer data sets including The Cancer Genome Atlas (TCGA), Pan-Cancer Analysis of Whole Genomes (PCAWG), and the Cancer Cell Line Encyclopedia (CCLE).
- apply findings from more than 6,000 analyzed samples to contextualize your own results and identify oncogene co-amplification patterns relevant to your cancer type of interest.