Combining multi-omics data and biological knowledge to extract disease mechanisms

About this Class

For our next CDSL webinar we will have a guest lecture by Dr. Julio Saez-Rodriguez from the Institute for Computational Biomedicine, Heidelberg. Bio: Julio Saez-Rodriguez is Professor of Medical Bioinformatics and Data Analysis at the Faculty of Medicine of Heidelberg University, director of the Institute for Computational Biomedicine, group leader of the EMBL-Heidelberg University Molecular Medicine Partnership Unit and a co-director of the DREAM challenges. He holds a PhD (2007) in Chemical Engineering. He was a postdoctoral fellow at Harvard Medical School and M.I.T (2007- 2010), group leader at EMBL-EBI, Cambridge (2010-2015), and professor of Computational Biomedicine at RWTH Aachen (2015-2018). His research focuses on computational methods to understand and treat the deregulation of cellular networks in disease (www.saezlab.org). Abstract: Multi-omics technologies, and in particular those with single-cell and spatial resolution, provide unique opportunities to study deregulation of intra- and inter-cellular processes in cancer and other diseases. In this talk I will present recent methods and applications from our group towards this aim, with a  focus is on computational approaches that combine data with biological knowledge.