Distinguished Speakers Seminar Series
Data-Driven Discovery of Secreted Proteins as Cancer Immunotherapies
Seminar Series Details:
About Peng Jiang PhD (NCI/CCR/CDSL)
Senior Investigator
Cancer Data Science Lab
Center for Cancer Research
NCI
About this Class
Dr. Jiang’s research focuses on developing data-integration and artificial intelligence frameworks to study intercellular signaling mediated by secreted proteins in anti-tumor immunity. Data-driven analyses estimate that about two thousand human genes encode secreted proteins. Yet, literature mining reveals that 61% of these genes lack known roles in cancer. To address this gap, his lab developed computational methods and applied diverse immunological models to dissect cytokine networks, secreted proteins, and ligand–receptor interactions in cancer. Ultimately, the labs’ goal is to uncover new mechanisms of immune regulation and identify therapeutic opportunities that harness intercellular communication against tumors.