About this Class

With the advancements in single cell and spatial profiling technologies and methods, some of us thought it would be helpful to re-establish a community of end users on campus. We invite those that are interested to attend an introductory meeting Wednesday (Sept 6^th, 2023). This users group aims to coordinate a regular schedule of presentations and discussion meetings where we can present our work in a friendly environment and discuss common hurdles that we may encounter in the implementation of these technologies and in our research.

Overall: The meeting format will be “lightning talks” (~ 5 minutes each) to get a taste of some of the spatial profiling applications being used at NIH. Following the talks, there will be light refreshments and everyone is welcome to stay and chat with colleagues.

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 Our fantastic speaker line-up:

 “Single-cell Spatial-Transcriptomic Analysis Revealed Leukemia-immune cell interactions in Refractory and Relapsed AML Patients Receiving Pembrolizumab and Decitabine”

Speaker: Chen Zhao, NCI-CCR

“Detecting Viral Transcripts with Spatial Profiling in Kaposi Sarcoma Patient Samples”

Speaker: Joe Ziegelbauer, NCI-CCR

“Spatial Transcriptomic Profiling of the Immune Response to Toxoplasma gondii Infection in the Brain”

Speaker: Alex Clark, NCI-CCR

“Spatial Transcriptomics to Evaluate Heterogeneity of Basal Forebrain Cholinergic Neurons”

Speaker: Mala Ananth, NINDS

“Single-cell Spatial Transcriptomic Technologies Reveal Cell Type-specific Changes in a Mouse Model of a-Synucleinopathy”

Speaker: Liam Horan-Portelance, NIA

“Spatial Protein Detection Technologies Easily Accessible at NIH”

Speaker: Noemi Kedei, NCI-CCR

“Pooled Optical Phenotyping for Functional Genomics Screens”

Speaker: Gianluca Pegoraro, NCI-CCR

“The Onset of Multiple Sclerosis-like Lesions in Marmoset Brain Through the Lens of Longitudinal MRI, Digital Histopathology, and Spatial Transcriptomics.”

Speaker: Jing-Ping Lin, NINDS

So, if you are currently working on a “single cell or spatial project” or are considering one and want to share and discuss experiences with others on campus, please join us for this introductory meeting. Based on those that we have talked to, this community will benefit from the different backgrounds and experiences that covers a broad array of different technologies, platforms, and methods of analysis - particularly in the spatial profiling domain. We hope to help organize forums and meetings to complement other group and community efforts, just as the single cell community has with other groups and scientific interest groups. 

 For those that cannot attend in person and still would like to participate, you will find WebEx access information below. Note that it will ask you to register (free) and provide your name and email.

 WebEx Access Info:

Topic: Single Cell and Spatial Users Group Intro Meeting

Date and Time: Wednesday, Sept 6th, 2023 10:00 am, Eastern Daylight Time (New York, GMT-04:00)

Event number: 2301 014 8729

Event password: W32RfVE39V$

Web Access: https://cbiit.webex.com/weblink/register/r5959c51a2bcc1b0831aa111e559dcb67

Audio-Only Access:

Call-in: 1-650-479-3207

Access code: 2301 014 8729