Quantifying Tumor Heterogeneity Using Single-Cell and Spatial Sequencing

About this Class

Please join us on March 23 when Ben Raphael, Ph.D., will present “Quantifying Tumor Heterogeneity Using Single-Cell and Spatial Sequencing.” In this presentation, Dr. Raphael will describe computational approaches to quantify tumor heterogeneity and reconstruct tumor evolution using data from single-cell DNA and spatial RNA sequencing technologies. He will also explain how tumors are heterogeneous mixtures of normal and cancerous cells with distinct genetic and transcriptional profiles. Dr. Raphael is a professor at Princeton University where he develops algorithms and mathematical models for addressing biological problems. His major areas of interest include computational cancer genomics, human structural variation, and comparative genomics.