ncibtep@nih.gov

Bioinformatics Training and Education Program

Somatic and Germline Copy Number and Sequence Variant Analysis Using Nexus Software

Somatic and Germline Copy Number and Sequence Variant Analysis Using Nexus Software

 When: May. 28th, 2013 2:30 pm - 4:00 pm

To Know

Where:
Building 37, Room 4041/4107
Organizer:
BTEP
This class has ended.
Video Archive *Class recordings may take ~48 hours to become available.

About this Class

Nexus Copy Number is a user-friendly desktop application for analysis and visualization of structural variation (copy number, allelic events, and small sequence variations) from CGH and SNP array- and NGS-generated data. The simple and interactive user interface allows for quick review of CNV/LOH/seq. variant results, annotation of samples, and customized report generation. All major statistical methods and algorithms that have become accepted as standards of practice in the field are incorporated into an intuitive, easy-to-use workflow for robust and straightforward analysis.
This seminar will highlight the following:

  1. Platform Independent Copy Number Analysis and Visualization
    • Affymetrix
    • Agilent
    • Illumina
    • Exome/Genome Sequencing
    • Other
  2. Co-visualization of Sequence Variation
    • Exome
    • Genome
    • Targeted
  3. Powerful Statistical Analysis Methods
    • Group Comparison
    • Concordance
    • Survival
    • Gene Enrichment
    • Clustering
    • Predictive Power
  4. Query for Aberrations in Nexus DB
    • TCGA
    • GEO
    • ISCA/ICCG

CCR currently has a number of floating licenses for Nexus software