Variant Analysis: Experimental Design, Best Practices and Workflows
When: Jun. 30th, 2022 2:00 pm - 4:00 pm
To Know
Where:
Online Webinar
Organizer:
BTEP
Presented By:
Justin Lack (NIAID CBR), Keyur Talsania (Bioinformatics Analyst IV, ABCS FNLCR)
About this Class
Experimental Design Considerations in Variant Analysis
- Germline vs Somatic
- WGS vs WES
- Sample sizes and statistical power
- QC, variant annotation, and analysis considerations
Beyond GATK!
- A survey of variant calling tools
- The actual Best Practices for variant calling
- Long read technology and germline variant calling
- Tumor vs tumor-normal: performance and considerations
Structural variants
· Long-read approaches for SV discovery/current WGS/WES Best Practices workflow