Single-Cell and Spatial Omics Seminar Series
From One Cell to Multiple Molecular Views: A Practical Introduction to Single-Cell Multi-omics
Seminar Series Details:
About Stefan Cordes, M.D., Ph.D. (NHLBI)
Stefan Cordes, MD, PhD
Assistant Clinical Investigator
National Heart, Lung, and Blood Institute, NIH
About this Class
This session will introduce major concepts and practical workflows for single-cell multi-omics, with emphasis on paired same-cell measurements such as CITE-seq and single-cell RNA+ATAC multiome, as well as integration of unpaired and spatial modalities. We will discuss how transcriptomic, protein, chromatin-accessibility, genotype/repertoire, perturbation, and spatial readouts can be combined to improve cell-state annotation and biological interpretation, with practical examples comparing Seurat/Signac and scverse-oriented workflows.